The complete trial platform


Clinical trials' biggest problems all share the same root cause.

85% of Clinical Trials Are Delayed

Enrolment takes years. Participants disengage. Coordinators drown in admin. Promising therapies wait while paperwork stalls progress. Phase III delays cost $600K–$8M per day.

Patients Juggle 5+ Apps

To talk to their own care team. GPs, specialists, allied health, mental health — all on different platforms. Messages get lost. The patient becomes the messenger. Care falls through the gaps.

Your command center. Their companion app.

"We built Flusso because clinical trials shouldn't be this hard — for anyone on either side."

What Your Team Sees in Participate

AI extracts protocol arms, endpoints, eligibility from PDF in minutes — not weeks of manual entry.

Survey instruments and ePRO schedules push to participants as notifications — completed in under 3 minutes.

Retention dashboards and risk alerts deliver predictive flags before disengagement happens.

Multi-site coordination and audit trails provide real-time visibility across every site, simultaneously.

What Participants Experience in Engage

One app for GP, specialists, and their trial — no new download, no portal to forget. Their existing healthcare routine.

Surveys as smart notifications, not email attachments — feels native, part of their daily routine.

Plain-language consent — "Your heart rate data monitors medication safety." Transparency that builds trust.

Full visibility into who sees their data — trust through transparency is what turns 70% retention into 85%+.

Participate: For clinical trials that patients complete.

TRIAL MANAGEMENT

Configurable protocol workflows with real-time amendment tracking and regulatory-grade audit trails from first patient in to database lock.

SITE OPERATIONS

Multi-site coordination with performance dashboards, enrollment analytics, and decentralized trial support across geographies.

SMART DATA CAPTURE

Electronic consent, patient-reported outcomes, and context-aware surveys that cut coordinator admin burden in half.

AI INTELLIGENCE

Participant-trial matching, dropout risk prediction, and automated protocol extraction — 15 operational AI features built in, not bolted on.

PARTICIPANT RETENTION

Trial discovery, gamification, and end-to-end encrypted messaging that directly attack the industry's 30% dropout problem.

PRIVACY BY ARCHITECTURE

Contextual Integrity embedded at every layer — compliant data collaboration by design, not by paperwork.

Engage: Our patient communication platform.

"The digital gateway to achieve your healthcare goals"

  • Survey responses - before, during, and after clinical trials and studies
  • Portable patient narrative
  • Linking at-risk patients with non-clinical health services prior to hospital discharge
  • End-to-end encrypted messaging
  • HIPAA-compliant video calls (WebRTC)
  • Multidisciplinary care team coordination
  • Patient communities for shared conditions
  • Clinical trial discovery and enrolment
  • Enduring patient engagement beyond trials
  • Wearable device integration

Built with Flutter for iOS and Android

Data Coalitions: To collaborate without compromise.

COALITION GOVERNANCE

Multiple organisations establish shared data norms once, then collaborate on every future request without renegotiating.

CONTEXTUAL INTEGRITY ENGINE

Built on a 20-year academic framework with 5,000+ citations — privacy violations aren't just flagged, they're architecturally impossible.

AUTOMATED STEWARDSHIP

Data sharing agreements that take 18+ months today close in weeks, with every request evaluated against governance norms in milliseconds.

DATA MARKETPLACE

Publish, discover, and access governed data products with tiered pricing — turning cross-org data collaboration into a revenue stream.

MULTI-JURISDICTION COMPLIANCE

HIPAA, GDPR, PIPL, and PDPA enforced through a single framework with immutable, regulator-ready audit trails.

CROSS-INDUSTRY INFRASTRUCTURE

Healthcare proves the architecture; mining, financial services, and government adopt proven infrastructure.

Perfect for cross-border trials, research networks, and pharma partnerships.

Three products on one privacy-first foundation.

Engage

One secure inbox for patients and their care team. Surveys, messages, and reminders in the app they trust. Free for patients.

Participate

End-to-end clinical trial and study management. From protocol PDF to configured trial in minutes. Your AI-powered command center.

Data Coalitions

Collaborate on data across organizations without it ever leaving your systems. Agree on governance once—share forever.

One app. Every conversation. No new portal to forget.

Unified Care Team Inbox

GP, specialists, allied health, mental health — one encrypted thread per patient. No more faxes or phone tag.

End-to-End Encryption

Olm protocol. Keys on device only. Even Flusso can't read messages. No other clinical platform offers this.

Clinical Trial Discovery

Patients swipe through trials matched to their health profile. Recruitment happens where patients already are.

Wearable Integration

Apple Health, Fitbit, Oura data feeds eligibility screening and monitoring. Contextual consent for every flow.

Gamification

Points, badges, streaks. Designed to drive survey completion rates above industry benchmarks by making participation feel rewarding, not burdensome.

Accessibility-First

Offline support, voice input, large text, 48px touch targets. Designed for the people most often left out.


Protocol PDF → Your workflows made easier

AI Protocol Import

Drop a PDF or DOCX. AI extracts arms, endpoints, eligibility, randomisation — with confidence scoring. You verify; you don't rebuild. Saves 2–4 weeks of setup.

Full Protocol Management

ICH E6(R3) aligned. Arms, randomisation, objectives, endpoints, IRB tracking, site monitoring, protocol deviations — all in one platform.

Observational Studies

Dedicated workflows for observational and longitudinal research. Not forced into trial workflows for non-interventional work.

Shared Surveys Library

Build once, deploy across any trial or study. Clone, version, share across your entire portfolio with zero duplication.

AI Recruitment Engine

Eligibility pre-screening, diversity dashboards, wearable-based qualification. Patients matched and reached via Engage.

REDCap Sync

Bidirectional integration via Flusso Connect. Use both platforms without double entry. No disruption to existing workflows.

Privacy isn't about restriction. It's about appropriate flow.

The root cause of complexity in managing clinical trials isn't technology. It isn't regulation. It's that current systems force an impossible choice: lock data down (killing innovation) or share freely (killing trust).

There has never been a middle ground — until now.

This is Contextual Integrity (CI)— a privacy framework developed over 20 years at Cornell Tech by Professor Helen Nissenbaum. Over 5,000 academic citations across law, computer science, and public policy. We turned it into production infrastructure.

Validated Before It Happens

Every data flow is validated against contextual norms before it happens.

Technically Impossible

Violations aren't against policy — they're technically impossible. The system itself prevents them. No policy gaps. No human errors. No misconfigured permissions.

Same Patient Data — Different Contexts — Different Rules

  • ✓ Doctor shares test results with specialist — Appropriate
  • ✓ Researcher accesses de-identified outcomes — Appropriate
  • ✓ Insurer receives relevant billing codes — Appropriate
  • ✗ Marketer accesses patient records — Blocked architecturally

Share data across organisations. The data never leaves.

Governance-First Architecture

Coalition members agree on sharing norms once. Every subsequent request is auto-validated. 80% pre-approved instantly. Legal friction eliminated by design.

No PII Custody

Data stays in your systems. Only governance rules flow between organisations. Zero breach liability — because there is no data processing.

CI Elements Engine

Define activities, attributes, subjects, roles, norms, and transmission principles. Visual configuration — not legal documents.

Data Marketplace

Register, tag, version, and publish data assets. Access requests with governance evaluation. Organisations earn revenue from their data contributions.

AI Sensitivity Detection

Automated classification per context — the same data may be sensitive in one context and entirely appropriate in another. Context-aware, not field-locked.

Cross-Border Compliance

HIPAA, GDPR, PDPA, PIPL built in. Regulatory changes become configuration updates, not architecture rebuilds.

Governance that travels. Data that doesn't. Your legal team will approve sharing on this platform that they'd never greenlight anywhere else — because violations are architecturally impossible, not just against policy.

When governance travels, everything changes.

Use Case 1

Multi-Site Rare Disease Research

Five hospitals. Twelve patients each — nowhere near statistical significance alone. With Data Coalitions, they form a governed research network in weeks, not years. Participants are already on Engage. Trial workflows run through Participate. Combined cohorts of hundreds. No new legal agreements. The research that was impossible last year becomes routine this year.

Use Case 2

GP Network to Research Pipeline

A network of 200 GP practices joins a Data Coalition. Patients use Engage for care coordination. When a pharmaceutical company needs a diabetes cohort, coalition governance norms pre-approve the query. Eligible patients are surfaced through Engage with contextual consent. GPs refer in minutes, not weeks. Practices earn marketplace revenue.

Use Case 3

Cross-Border Phase III Trial

A trial spans Australia, Singapore, and Hong Kong. Each jurisdiction has different privacy laws. Participate manages the protocol. Engage keeps participants connected. Data Coalitions handle cross-border governance with CI norms that satisfy all three regulatory regimes simultaneously. Global trial data that actually globalises.

Security isn't a feature we added. It's how we're built.

Zero-Trust Encryption

End-to-end encryption via Olm protocol. Keys on device only. Flusso cannot read patient messages — by design, not by policy. No other clinical platform offers this level of security.

Contextual Integrity Architecture

82+ database tables implementing the CI framework. Three-tier governance evaluation engine. Violations aren't just against policy — they're architecturally impossible.

Regulatory Alignment

HIPAA, GDPR, PDPA, PIPL, NHMRC, ICH E6(R3), 21 CFR Part 11. Cross-border compliance built into the architecture. Regulation changes = configuration updates, not code changes.

Immutable Audit Trail

Every data access, consent decision, and governance evaluation — permanently logged. Ethics committee audits take hours, not weeks. NHMRC-compliant reports exportable on demand.

Responsible AI for Healthcare

Smart automation, human oversight.

For Research Teams

AI Protocol Import

PDF to configured trial with confidence scoring. Minutes, not weeks of manual setup.

Dropout Prediction

Flag participants at risk of disengaging before they leave. Intervene early, retain more.

AI Pre-Screening

Accelerate eligibility assessment. Surface promising candidates, flag exclusions automatically.

Protocol Variance Detection

Catch deviations automatically. Real-time compliance monitoring across every site.

For Participants & Coalitions

Trial Discovery

AI matching surfaces relevant trials based on health profile, location, and preferences.

Personalised Engagement

Reminders and content that adapt to individual preferences and schedules. Right time, right channel.

Contextual Classification

Automatically classify data sensitivity per context, not per field — the CI way.

Collaboration Recommendations

Surface compatible datasets and mutually beneficial partnerships across the coalition network.

One platform that does what no combination of competitors can.

From conversation to value in weeks.

Start with Participate

If your most pressing challenge is your next clinical trial — protocol setup, enrolment, or retention.

Start with Engage

If your priority is care coordination across a provider network or improving participant communication.

Start with Coalitions

If multi-site data collaboration or cross-organisational research is your most immediate bottleneck.

Governance That Travels, Data That Doesn't.

Three products. One governance layer. The platform that solves healthcare's trust problem — so patients complete trials, providers coordinate care, and organisations collaborate on research that was previously impossible.

Ready to see what becomes possible?

Schedule a Discovery Call

30 minutes. Tailored to your organisation's specific challenges — not a canned demo. We come prepared with your workflows in mind.

Visit flusso.ai

Explore product details, case studies, and the Contextual Integrity framework behind the platform.

Get in Touch

Email us at contact@flusso.ai​ and we will respond within one business day with a proposed agenda tailored to your team.